This actually has been reported on TP2 also, it seems that the HTC devices has a issue waking up from unit being suspended.... I think this is a power managment issue with 6.5 because I have the same issue with my Imagio but my way of resolving this was to disable the option under power settings that says "Turn off deviice if not used for" but leave the Backlight set to turn backlight off... Once I did this I havent seen this issue any more. Give it a try hopefully it works well for you also.
Oh yeah, I map one of front buttons to be able to turn backlight off when pressed.
Try this application here...
http://forum.xda-developers.com/showthread.php?t=569473